We worked on a number of puzzles, together as a family, during Grandma's visit.
Our favorites by far were a couple from the Bepuzzled Mystery Puzzle series (non-affiliate link). They turned out not only to be challenging puzzles (the picture on the box is not what the puzzle actually looks like),
There is no picture guide for the puzzle, as the completed picture contains clues to help you solve the mystery.
However, as details from the story are represented in the puzzle, the story also contains clues to help in piecing together the puzzle. The more attention you pay while reading the story, the easier it will be to put the puzzle together.
Once the puzzle is complete, you can scan the picture for clues to solve the mystery (you might need to reread the story, at this point to refresh your mind to any forgotten details), before reading the solution (printed upside down and backwards) to the story to see if your guess is correct.
There are a number of different puzzles in the series - even one based on a Sherlock Holmes mystery with the complete story by Sir Arthur Conan Doyle included (I couldn't have been more thrilled).
We found the 1000 piece puzzles were more suited to the teens, than the younger children in the family, but everyone enjoyed the stories. In fact, we had almost as much fun reading the story together, as we did in putting the puzzles together, and solving the mystery through the clues in the puzzle.
I really can't think of a better introduction to the mystery genre, especially for teen readers, and puzzle lovers in the family.